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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRIP2
All Species:
20.91
Human Site:
S586
Identified Species:
46
UniProt:
Q9C0E4
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C0E4
NP_001073892
1043
112501
S586
R
G
E
P
L
I
I
S
D
I
K
K
G
S
V
Chimpanzee
Pan troglodytes
XP_516302
1233
132862
S776
R
G
E
P
L
I
I
S
D
I
K
K
G
S
V
Rhesus Macaque
Macaca mulatta
XP_001090379
1196
128788
S739
R
G
E
P
L
I
I
S
D
I
K
K
G
S
V
Dog
Lupus familis
XP_541752
1043
112509
S586
R
G
E
P
L
I
I
S
D
I
K
K
G
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q925T6
1127
122039
I601
K
P
G
D
P
L
V
I
S
D
I
K
K
G
S
Rat
Rattus norvegicus
Q9WTW1
1043
112470
S588
R
G
E
P
L
I
I
S
D
I
K
K
G
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521279
546
59112
P165
L
L
S
V
D
G
I
P
L
H
N
V
T
H
S
Chicken
Gallus gallus
XP_414383
1065
115083
S621
P
F
D
P
I
V
I
S
G
L
T
K
R
G
L
Frog
Xenopus laevis
A8E0R9
1083
118442
D598
G
E
P
L
I
I
S
D
I
K
K
G
S
V
A
Zebra Danio
Brachydanio rerio
XP_001922281
1044
114243
K608
I
I
Y
T
V
E
L
K
R
Y
G
G
P
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790732
1120
120152
I602
Q
V
L
A
I
D
D
I
H
L
D
S
I
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.2
84.8
92.5
N.A.
56.7
87.5
N.A.
41.5
69
67.6
57.9
N.A.
N.A.
N.A.
N.A.
41.2
Protein Similarity:
100
84
85.7
95.1
N.A.
70.9
92.1
N.A.
46.5
77.1
78.3
70.9
N.A.
N.A.
N.A.
N.A.
59.3
P-Site Identity:
100
100
100
100
N.A.
6.6
100
N.A.
6.6
26.6
13.3
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
26.6
100
N.A.
6.6
60
20
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
10
10
10
10
46
10
10
0
0
0
0
% D
% Glu:
0
10
46
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
46
10
0
0
10
0
0
10
0
10
19
46
19
10
% G
% His:
0
0
0
0
0
0
0
0
10
10
0
0
0
10
0
% H
% Ile:
10
10
0
0
28
55
64
19
10
46
10
0
10
0
0
% I
% Lys:
10
0
0
0
0
0
0
10
0
10
55
64
10
0
0
% K
% Leu:
10
10
10
10
46
10
10
0
10
19
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
10
10
10
55
10
0
0
10
0
0
0
0
10
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
46
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% R
% Ser:
0
0
10
0
0
0
10
55
10
0
0
10
10
46
19
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
10
0
10
10
0
% T
% Val:
0
10
0
10
10
10
10
0
0
0
0
10
0
10
55
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _